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Development of compounds to the stage of approval includes inherent risk at each stage of development that FDA in its discretion will mandate a requirement not foreseeable by us or by ALZA. There would also be testing delays if, for example, our sources of drug supply could not produce enough DPI-125 to support the then ongoing clinical trials being conducted. If this were to occur, it could have a material adverse effect on our ability to develop DPI-125, obtain necessary regulatory approval, and generate sales and cash flow from the sale of DPI-125. If delays in completion constitute a breach by ALZA, or if ALZA chooses to not continue development of DPI-125, then primary responsibility for completion may return to Enhance. There is no assurance that we would have the financial, managerial or technical resources to complete such tasks in timely fashion or at all. BECAUSE MANY OF OUR COMPETITORS HAVE SUBSTANTIALLY GREATER CAPABILITIES AND RESOURCES, THEY MAY BE ABLE TO DEVELOP PRODUCTS BEFORE US OR DEVELOP MORE EFFECTIVE PRODUCTS OR MARKET THEM MORE EFFECTIVELY WHICH WOULD LIMIT OUR ABILITY TO GENERATE REVENUE AND CASH FLOW.

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